p53 gain‐of‐function mutations increase Cdc7‐dependent replication initiation
نویسندگان
چکیده
منابع مشابه
The Prevalence of P53 Mutations in Laryngeal Cancer in Kerman
Background &Aims: Laryngeal cancer is the second common cancer of respiratory tract, following the lung cancer. Carcinogenesis is a complex multistage process; molecular genetics has provided the evidence that activation of proto-oncogene and loss or inactivation of tumor suppressor genes (TSG) are involved in a large number of malignancies. One of the earliest significant tumor suppressor gene...
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The theoretical relations between replication, initiation, termination, and deoxyribonucleic acid (DNA) accumulation were derived for experiments in which the length of the time required for the replication of the bacterial chromosome (C period) can be varied. This theory enables one to determine absolute values of the C period from kinetics of DNA accumulation after a "stepup" with thymine-req...
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ژورنال
عنوان ژورنال: EMBO reports
سال: 2017
ISSN: 1469-221X,1469-3178
DOI: 10.15252/embr.201643347